R-spondin-1 Fc fusion, human
规格:
数量:
价格:
折后价:
金牌价格:
联系客服:
产品英文名称:R-spondin-1 Fc fusion, human
产品中文名称:人重组R-spondin-1 Fc fusion蛋白
R-spondin-1 Fc fusion, human产品介绍:
R-spondin-1是权威WNT信号通路的天然增强剂。当与激活β-catenin信号通路的WNT蛋白联合使用时,R-spondin-1能通过与LGR5和LGR4融合而有效提高权威WNT蛋白的活性。
向小鼠注射重组R-spondin-1蛋白可以激活β-catenin信号通路和肠道下皮细胞的增殖,为临床改善化疗诱导结肠炎操作提供了基础和依据。
本产品是全片段R-spondin-1与人IgG1细胞Fc片段的C-终端相融合而得到的。这种融合保证了体内外蛋白的稳定性而不影响其生物活性。StemRD公司的R-spondin-1 Fc融合蛋白是由人293细胞作为分泌蛋白,并经过一系列的色谱分析法纯化而得到。
R-spondin-1 Fc fusion, human产品英文简述:
R-spondin-1 is a natural enhancer of the canonical WNT pathway. When used together with WNT proteins that activate the beta-catenin pathway, Rspondin- 1 enhances the activity of canonical WNT proteins by binding to LGR5 and LGR4 (refs.) Injection of recombinant R-Spondin-1 into mouse causes activation of the-catenin pathway and proliferation of intestinal crypt cells, which forms the basis for a clinical trial in amelioration of chemotherapy-induced colitis.
This product is the full-length R-Spondin-1 fused at its C-terminus to the Fc domain of human IgG1. This fusion increases the stability of the protein in vitro and in vivo without compromising its biological activity. StemRD’s R-Spondin-1 Fc fusion protein is produced in human 293 cells as a secreted protein and purified by protein A chromatography.
• Purity: Greater than 90% as determined by SDS-PAGE analysis
• Biological Activity: The activity was determined by using a TCF reporter gene assay in cultured
human cells. The EC50 ranges from 5 - 20 ng/ml in the presence of 10ng/mL human WNT-3a. Activity in other assays should be determined by each individual setting.
• For Research Use Only. Not for Use in Human
OriGen CP-70 CryoPur-DMSO 细胞冻存液 二甲基亚砜 进口USP级 CE认证 CP70
¥1Lifeline LL-0002 VascuLife EnGS Complete Kit 人内皮细胞培养基套装
¥1Anti-Human CD4 PerCP-Cyanine5.5 人CD4抗体
¥4,188Corning 88-571-kit Natural Killer Cell Serum-free Culture Kit II NK细胞活化扩增培养基套装
¥0Cellartis Y50200 MSC Xeno-Free Culture Medium 人间充质干细胞培养基,无外源无需包被
¥1Origen CS250 Freezing Bags vol-max 30-70mL 冻存袋 细胞治疗用药包材
¥1PerkinElmer 华雅现货代理 优势产品!
专门为iPSC 细胞治疗而开发的-康宁 354787 现货
升级您的iPSC细胞治疗研究 —— Corning SyntheGel基质胶系列
【新品】Tecan Revelo™ RNA-Seq High Sensitivity产品 优势 现货
探索SARS-CoV-2的奥秘:Revelo™ RNA-Seq High Sensitivity技术
Countstar Countstar Mira BF在类器官培养中利用
华雅思创生物代理Countstar:专业细胞成像分析设备的领先者
为什么选择康宁G418:细胞培养筛选的黄金标准
探索G418:细胞培养中的重要筛选工具
【器械大科普】采血管颜色与功能区别 BD现货代理!