Catalog Number :BGK9QYH9

LIGHT belongs to the TNF family of ligands, and can signal through the herpes virus entry mediator type A receptor (HVEM, TNFRSF14), LTβR, or bind to a decoy receptor, DcR3. It is expressed in splenocytes, activated PBL, CD8+ tumor infiltrating lymphocytes, granulocytes, and monocytes. LIGHT has the ability to active NF-κB, to co-stimulate the activation of lymphocytes and to induce apoptosis in certain human tumor cells.

The BioGems Murine Light Pre-Coated ELISA (Enzyme-Linked Immunosorbent Assay) kit is a solid phase immunoassay specially designed to measure Light with a 96-well strip plate that is pre-coated with mouse monoclonal antibody specific for Light. It contains NS0-expressed recombinant Light. The detection antibody is a biotinylated goat polyclonal antibody specific for Light. The kit is analytically validated with ready to use reagents.

LIGHT属于TNF配体家族，并且可以通过疱疹病毒进入介质A型受体（HVEM，TNFRSF14），LTβR或与decoy受体DcR3结合而传导信号。它在脾细胞，活化PBL，CD8 +肿瘤浸润淋巴细胞，粒细胞和单核细胞中表达。LIGHT可以活化NF-κB以共刺激淋巴细胞的活化并诱导某些人类肿瘤细胞的凋亡。

BioGems鼠Light预包被ELISA试剂盒是一种固相免疫分析试剂，专门设计用于检测Light，并在96孔微孔板上预包被Light特异性小鼠单克隆抗体。 它含有NS0表达的重组Light。 检测抗体是对Light特异的生物素化山羊多克隆抗体。该试剂盒经过分析验证，是即用型试剂。

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Reproducibility可重复性